

The purpose of this study is to learn more about the effects of similar weight loss through caloric restriction, gastric reduction, and bypass of the proximal small intestines on gut microbiota and compare them to changes in the microbiome of obese subjects undergoing sham procedures and life-style modification. Changes in Gut Microbiota after Endoscopic Procedures for the Treatment of Obesity.The purpose of this study is to evaluate a treatment for obesity. A Study for the Treatment of Primary Obesity.

The purpose of this study is to explore the effectiveness and safety of a modified gastroplication technique for weight loss in five patients with obesity, and includes physiologic appraisal of gastric emptying (via gastric emptying breath test) and post-prandial gastric accommodation (via SPECT). A Study to Evaluate the Effect of POSE2 on Long-term Gastric Motor Function.Investigators are doing this research study to find out the effect of T6 dermatomal electrical stimulation (delivered by a Transcutaneous Electrical Nerve Stimulation (TENS) unit) on appetite and weight loss. Dermatome Electrical Stimulation on Individuals With Overweight and Class I Obesity.The purpose of this study is to assess changes that occur in the intestine microbe environment of obese people as they perticipate in a structured diet and lifestyle modification. A Study of Changes to the Microbe Environment in the Intestines of Obese People who Modify Their Diet and Lifestyle.The purpose of this study is to determine if culturally-relevant interventions will decrease obesity in underserved Hispanic children and help those children learn lifelong healthy habits. A Study to See if Culturally Relevant Interventions Decrease Obesity in Hispanic Children.Finally, the study will examine the relations of adolescent- and parent-reported motivators and level of motivation for weight loss with adolescents’ healthful and unhealthful weight management strategies and BMI. The study will compare motivators and level of motivation for adolescent weight loss between adolescents and parents and across care sites (i.e., primary care vs. This study aims to examine associations of social support for healthful eating and physical activity with adolescents’ healthful and unhealthful weight management strategies and body mass index (BMI). Social Support and Motivators for Adolescent Weight Loss.The purpose of this study is to determine the turnover rate of motor protein isoforms (myosin heavy chain, MHC) and overall muscle protein in skeletal muscle of subjects with obesity and lean controls in the basal state, and to determine stimulation of the turnover rate of motor protein (MHC isoforms) in skeletal muscle of subjects with obesity and lean controls by plasma amino acids and with and without prior exercise. Regulation of Muscle Protein Phenotype in Humans with Obesity.The aim of this study is to assess the quality of life among a sample of obese liver transplant recipients and compare it between those who underwent sleeve gastrectomy and those who did not. Quality Of Life after Simultaneous Sleeve Gastrectomy and Liver Transplantation.ORBERA™ is a special balloon approved by the FDA for overweight adults, and we would like to try using it for overweight teenagers. We want to learn if older teenagers who are overweight will lose weight and if their other medical problems will get better. The reason we are doing this research is to get information about the ORBERA™ Intragastric Balloon to learn if it is safe and if it works. Intragastric Balloon in Obese Adolescents With Comorbidities.The purpose of this research is to establish the normal range of diameter and distensibility of pylorus and the fasting and postprandial antro-pyloric motility in healthy male and female adults. A Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers.The primary aim is to study the correlation between changes in the gut microbiome of obese subjects undergoing an intragastric balloon procedure. Changes in Gut Microbiota After Placement of Endoscopic Intragastric Balloon.This research study is being performed to find out if a new device, AspireAssist Aspiration Therapy System, can help people with obesity to lose weight without causing too many side effects. Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study.A prospective, multicenter, open-label, post-approval study of the safety and effectiveness of ORBERA™ as an adjunct to weight reduction for obese adults (22 years of age and older) with a Body Mass Index (BMI) of ≥ 30 kg/m2 and BMI ≤ 40 kg/m2
